Clustered Gene Expression Changes Flank Targeted Gene Loci in Knockout Mice
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چکیده
منابع مشابه
Clustered Gene Expression Changes Flank Targeted Gene Loci in Knockout Mice
BACKGROUND Gene expression profiling using microarrays is a powerful technology widely used to study regulatory networks. Profiling of mRNA levels in mutant organisms has the potential to identify genes regulated by the mutated protein. METHODOLOGY/PRINCIPLE FINDINGS Using tissues from multiple lines of knockout mice we have examined genome-wide changes in gene expression. We report that a si...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2007
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0001303